Patient Drug Information & Medication Resource Guide

SemaMelt Plus No Caffeine

SemaMelt Plus is a compounded oral dissolvable tablet (ODT) designed to tackle appetite and cravings from multiple angles.

Formulation

Tablet Description

Impressions may vary depending on dosages.

SemaMelt Plus white tablet

Mint Flavor, White

Semaglutide 2.75mg + Naltrexone HCL 3mg

Semaglutide 2.75mg, Naltrexone HCL 3mg, 10mm, Mint Flavor, White

SemaMelt Plus green tablet

Mint Flavor, Green

Semaglutide 5mg + Naltrexone HCL 5mg

Semaglutide 5mg, Naltrexone HCL 5mg, 10mm, Mint Flavor, Green

How Does It Work

This unique combination targets appetite control through hormonal, neurological, and metabolic mechanisms:

  • Semaglutide: A GLP-1 receptor agonist that promotes fullness, slows gastric emptying, and reduces food cravings. It helps regulate insulin and glucose, supporting long-term fat loss and metabolic stability.
  • Naltrexone: A low dose opioid receptor modulator that reduces reward-driven eating behaviors and emotional cravings. When used in weight loss, it supports appetite reduction and may improve adherence to dietary goals.

Benefits of SemaMelt Plus

  • Reduces Appetite and Emotional Cravings
  • Enhances Satiety and Glucose Control
  • Non-injectable, Fast-Dissolving, and Easy to Use

Directions for Use

Place one ODT under the tongue and allow it to fully dissolve. Best taken in the morning or as directed by your healthcare provider. Avoid food or drink for at least 30 minutes after dosing to maximize efficacy.

Potential Side Effects

  • Semaglutide: Nausea, constipation, or bloating
  • Naltrexone: Headache or mild GI discomfort

Who Should Not Use SemaMelt Plus

  • Individuals with a personal or family history of medullary thyroid carcinoma (MTC)
  • Patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Those taking opioid medications or with opioid dependence
  • Pregnant or breastfeeding individuals

How do I store and/or dispose of this drug?

Store at room temperature. Protect from light. Avoid exposure to high humidity (keep container tightly closed). Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain. Check with your pharmacist if you have questions about how to throw out drugs. Do not share your drugs with others and do not take anyone else’s drugs. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-888-463-6332 or at https://www.fda.gov/medwatch.

Exclusively Made By EPIQ SCRIPTS

Epiq Scripts is a URAC- and ACHC/PCAB-accredited compounding pharmacy, committed to the highest standards of safety, quality, and regulatory compliance. All ingredients are sourced exclusively from FDA-registered and inspected wholesalers to ensure pharmaceutical-grade purity and efficacy. Our compounds are crafted with precision in a state-of-the-art facility adhering to strict USP guidelines.